I wanted to check whether it is possible to use the @uppy/aws-s3-multipart plugin (https://uppy.io/docs/aws-s3-multipart/) to upload to digital ocean’s spaces? I saw in the documentation for the non-multipart s3 plugin (https://uppy.io/docs/aws-s3/#DigitalOcean-Spaces) that that plugin supports s3, but not sure whether the same approach would work for multipart plugin.
I had the same situation you described.
You need to set the correct CORS configuration in your bucket. For that you can upload a configuration file to Digital Ocean by s3cmd.